Preety Panwar

This study identifies Cathepsin K as a key host protease for SARS-CoV-2 spike activation and shows it can be inhibited by existing drugs.

This paper demonstrates that lysosomal cysteine cathepsins can generate fusion peptides through reverse proteolysis, revealing a new dimension of protease activity and peptide diversification.

This paper shows cathepsin K inhibitors enhance osteoclast-osteoblast communication and promote osteogenesis, suggesting their unique role in balancing bone resorption and formation.

This study shows osteoclasts contribute to pain in arthritis by affecting bone vascularization and innervation, and inhibitors can reverse this pain.