Author

Eric Chan

Memorial Sloan Kettering Cancer CenterORCID 0009-0002-2835-3994Unclaimed ORCID profile · follow to get notified of new preprints

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Eric Chan6 papers · Memorial Sloan Kettering Cancer Center

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Afşar BarlasiD· 1 shared Elisa de StanchinaiD· 1 shared Hongyan LiiD· 1 shared Jacob A. BoyeriD· 1 shared Katia O Manova-TodorovaiD· 1 shared Malvika SharmaiD· 1 shared Marcus BosenbergiD· 1 shared Michael OverholtzeriD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Afşar BarlasORCID

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1 paper

Recent·Most cited

Cancer BiologyCancer ResearchPeer-reviewedFeb 24, 2025

Tumorigenesis driven by the BRAF V600E oncoprotein requires secondary mutations that overcome its feedback inhibition of migration and invasion

Sunyana Gadal, Jacob A. Boyer, Simon F. Roy…·Neal X. Rosen

This study shows that BRAFV600E mutations inhibit cell migration and invasion through feedback inhibition of RAC1, requiring secondary mutations to overcome this block and enable tumorigenesis.

7 citations

humanDNA methylation

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