Author

Saugat Pokhrel

University of California, San FranciscoORCID 0009-0002-3964-5327Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Abby Oehler· 1 shared Aye C. ThwiniD· 1 shared Charles S. CraikiD· 1 shared Cory M. NadeliD· 1 shared Daniel A. MordesiD· 1 shared Daniel R. SouthworthiD· 1 shared Jason E. GestwickiiD· 1 shared Koli Basu· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Abby Oehler

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedSep 12, 2024

Phosphorylation of a Cleaved Tau Proteoform at a Single Residue Inhibits Binding to the E3 Ubiquitin Ligase, CHIP

Cory M. Nadel, Saugat Pokhrel, Kristin Wucherer…·Jason E. Gestwicki

This study identifies phosphorylation at residue S416 on tauC3 as a mechanism that inhibits its degradation by CHIP, contributing to its accumulation in Alzheimer's disease.

33 citationstop 4%

humanproteomics

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