Author

Jessica N. Becerra

Fred Hutch Cancer CenterORCID 0009-0002-4111-4832Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Ashley V. DiMarcoiD· 1 shared Brock J. McKinneyiD· 1 shared Feinan WuiD· 1 shared James V. AlvareziD· 1 shared Matthew FitzgibboniD· 1 shared Nina Marie G. GarciaiD· 1 shared Sharan SrinivasaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Ashley V. DiMarcoORCID

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1 paper

Recent·Most cited

Cancer BiologyCancer Research CommunicationsPeer-reviewedMay 1, 2025

APOBEC3 activity promotes the survival and evolution of drug-tolerant persister cells during acquired resistance to EGFR inhibitors in lung cancer

Nina Marie G. Garcia, Jessica N. Becerra, Sharan Srinivasan…·James V. Alvarez

This study shows APOBEC3 activity supports drug-tolerant persister cells in EGFR inhibitor-resistant lung cancer by promoting transdifferentiation and mutation acquisition.

23 citationstop 1%

humanDNA methylation

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