Tianyi Hou

The study identifies SKSR1 as a key virulence factor in Cryptosporidium by crossing isolates with different virulence and analyzing genetic loci associated with infectivity.

The paper investigates the role of GP60 in Cryptosporidium parvum infectivity, finding that while GP60 is not essential, its cleavage products affect parasite growth and infection severity.

This paper develops a method to cultivate and cryopreserve Cryptosporidium hominis and C. parvum using enteroids, showing improved transcriptomic responses compared to conventional cell systems.