Cell BiologyNature Chemical BiologyPeer-reviewed
Small molecule modulation of a redox-sensitive stress granule protein dissolves stress granules with beneficial outcomes for familial amyotrophic lateral sclerosis models
Hiroyuki Uechi, Sindhuja Sridharan, Jik Nijssen…·Richard John Wheeler
The paper identifies lipoamide as a small molecule that dissolves stress granules and improves outcomes in ALS models by modulating redox-sensitive proteins.
146 citationstop 1%