NeurosciencebioRxivPreprint
The Icelandic mutation APPA673T on amyloid-β plaque burden in the 5xFAD Alzheimer model
Anne Anschuetz, Renny Listyono, Thomas Vorley…·Karima Schwab
This study investigates the effect of the APPA673T mutation on amyloid-β plaque burden in 5xFAD mice, finding a significant reduction in plaque size but not in soluble Aβ levels.
DOI 10.1101/2025.11.05.686739