Anthony J. Clark

This study assesses the 4-week immunotoxicity and toxicokinetics of lactoferrin alpha produced by Komagataella phaffii in rats, finding no toxicologically significant changes at high doses.

The paper assesses the allergenic risk of recombinant human lactoferrin produced in Komagataella phaffii using bioinformatics, glycan analysis, and simulated digestion, finding low allergenic potential.

This study evaluates the oral toxicity of recombinant human lactoferrin in rats at various doses, finding it well-tolerated up to 2000 mg/kg/day.

This study characterizes recombinant human lactoferrin produced in yeast, confirming its sequence, purity, glycosylation, structure, and thermal stability similar to native human milk lactoferrin.