MicrobiologymBioPeer-reviewed
Gene editing of SAMHD1 in macrophage-like cells reveals complex relationships between SAMHD1 phospho-regulation, HIV-1 restriction and cellular dNTP levels
Moritz Schüssler, Kerstin Schott, Nina V. Fuchs…·Renate König
This study uses CRISPR/Cas9 to edit SAMHD1 in macrophage-like cells, revealing that T592 phosphorylation affects HIV-1 restriction and dNTP levels independently.
11 citations