Author
University of VirginiaORCID 0009-0002-9770-5594Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Chunsong Yang, Krzysztof Wierbiłowicz, Hyukjin Jang…·Bryce M. Paschal
This study identifies an ADP-ribosyl-cysteine degron in PARP7 that is recognized by DTX2, leading to PARP7 degradation and affecting AR signaling in prostate cancer.
Krzysztof Wierbiłowicz, Chunsong Yang, Ahmed Almaghasilah…·Bryce M. Paschal
The paper identifies PARP7 as an enzyme that ADP-ribosylates the androgen receptor, marking it for degradation and creating negative feedback on AR-dependent gene expression.
Carlos Vela‐Rodríguez, Chunsong Yang, Heli I. Alanen…·L. Lehtiö
This study identifies the D2 domain of DTX3L as critical for forming oligomeric complexes that enable the DTX3L-PARP9 complex to read mono-ADP-ribosylated androgen receptor.
Karolina Sienkiewicz, Chunsong Yang, Bryce M. Paschal, Aakrosh Ratan
The paper reports genomic analyses of prostate cancer cell lines, identifying mutations and chromothripsis events associated with TP53 inactivation.