Adi Cohen

The paper develops cell-permeable C16orf74 peptides that disrupt Calcineurin-NFAT interaction, inhibit T-cell activation, and show minimal cytotoxicity compared to Cyclosporine A.

This paper describes the engineering of a bispecific fusion protein combining CTLA-4 and IL-10 to modulate immune checkpoints and cytokine receptors, showing T cell-inhibitory effects in vitro.

This paper engineers methionine-auxotroph E. coli by evolving enzymes from C. glutamicum to enable growth in minimal medium.

The paper examines brain volumetric changes in a population before and after the COVID-19 outbreak and lockdown, finding increases in amygdala, putamen, and anterior temporal cortices, which diminished over time.