Maayan Gal

This study inhibits prolyl hydroxylase to enhance collagen type I production in mouse cells under normoxia, achieving a 29-fold increase.

The paper develops cell-permeable C16orf74 peptides that disrupt Calcineurin-NFAT interaction, inhibit T-cell activation, and show minimal cytotoxicity compared to Cyclosporine A.

This paper describes the engineering of a bispecific fusion protein combining CTLA-4 and IL-10 to modulate immune checkpoints and cytokine receptors, showing T cell-inhibitory effects in vitro.

This paper shows that liver-specific methylation sites regress toward a pan-tissue average during aging and disease, and this loss can be partially reversed by fasting.

This paper evaluates a FRET-based biosensor for real-time pH monitoring as an indicator of food spoilage, showing pH-responsive signals in both buffer solutions and chickpea paste.

The paper develops a fluorescence lifetime-based sensor to image autophagy dynamics in vivo, revealing spatial and activity-dependent patterns in the mouse brain.

This study investigates psoriasin as a natural food preservative, showing its antimicrobial activity and potential for cost-effective production.

The paper shows that epigenetic information loss, characterized by degradation of tissue-unique methylation patterns, occurs in multiple diseases and aging.

This paper develops a genetically encoded biosensor for dynamically monitoring PTEN activity in living cells and tissues with high spatial and temporal resolution.

This study identifies small molecule inhibitors targeting the PPI complex of OASS and SAT, offering a new mode of action for herbicides.

This study evaluates psoriasin's ability to inhibit Candida albicans growth on denture bases, finding it effectively eradicates fungal growth when applied to the material.

This paper engineers methionine-auxotroph E. coli by evolving enzymes from C. glutamicum to enable growth in minimal medium.

This study evaluates a 16-residue peptide from Medicago truncatula defensin for its ability to penetrate mammalian cells and deliver cargo, showing efficient uptake and minimal cytotoxicity.