Author

Kaste Jurgaityte

Hammersmith HospitalORCID 0009-0004-4356-6677Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Abhay KotechaiD· 1 shared Adrian F. Koh· 1 shared Alejandra TomásiD· 1 shared Andrew M. James ShapiroiD· 1 shared Ash K. BahliD· 1 shared Basil J. GreberiD· 1 shared Eva Kane· 1 shared Guy A. RutteriD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Abhay KotechaORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintApr 7, 2023

High-resolution cryo-electron microscopy of the human CDK-activating kinase for structure-based drug design

Victoria I. Cushing, Adrian F. Koh, Junjie Feng…·Basil J. Greber

The paper determines high-resolution structures of CDK-activating kinase using cryo-EM, revealing inhibitor interactions and providing a framework for structure-based drug design.

4 citations

humanprotein structure

𝕏 PostBluesky

GenomicsbioRxivPreprintOct 1, 2019

β-cell dedifferentiation is associated with epithelial-mesenchymal transition triggered by miR-7-mediated repression of mSwi/Snf complex

Tracy C S Mak, Yorrick von Ohlen, Yi Fang Wang…·Mathieu Latreille

This study identifies miR-7-mediated repression of Brg1 as a driver of β-cell dedifferentiation through EMT, leading to fibrosis and impaired glucose tolerance in diabetes.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky