GenomicsBMC BiologyPeer-reviewed
Single-cell DNA and RNA sequencing reveals the dynamics of intra-tumor heterogeneity in a colorectal cancer model
Hanako Ono, Yasuhito Arai, Eisaku Furukawa…·Mamoru Kato
This study uses single-cell DNA and RNA sequencing to analyze intra-tumor heterogeneity dynamics in a mouse colorectal cancer model, finding increased RNA heterogeneity and decreased DNA heterogeneity after transplantation.