Author

Prince Upadhyay

Shiv Nadar FoundationORCID 0009-0004-9490-0831Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1

Frequent Co-Authors

S Shyamkishor SinghiD· 4 shared Soumya PatiiD· 4 shared Soumyadeep MukherjeeiD· 4 shared Abir MondaliD· 3 shared Isha Saxena· 2 shared Akshay Munjal· 1 shared Animesh SamantaiD· 1 shared Arushi SharmaiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersCell Biology

S Shyamkishor SinghORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BiochemistrybioRxivPreprintApr 30, 2026

Dynamic s-acylation of schizophrenia-linked antioxidants explicate the redox flexibility of human microglia during inflammation.

Soumyadeep Mukherjee, Arushi Sharma, Prince Upadhyay…·S Shyamkishor Singh

This study identifies inflammation-responsive s-acylation of key antioxidants in microglia, revealing their role in redox flexibility and schizophrenia pathology.

DOI 10.64898/2026.04.28.721236

humanproteomics

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Cell BiologybioRxivPreprintFeb 5, 2025

Monoclonal antibody to Filarial serpin Wb123 impedes the urokinase plasminogen activator receptor-mediated Alternative activation of macrophages

Prince Upadhyay, Akshay Munjal, Abir Mondal…·Shailja Singh

This study identifies the filarial serpin Wb123 and shows it promotes macrophage alternative activation via uPAR, which is inhibited by the monoclonal antibody MAbG8.

DOI 10.1101/2025.02.05.636671

experimental assayhost-pathogen & immune response

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Pharmacology & ToxicologyHeliyonPeer-reviewedFeb 1, 2025

Enhancing NADPH to Restore Redox Homeostasis and Lysosomal Function in G6PD-Deficient Microglia

Abir Mondal, Soumyadeep Mukherjee, Prince Upadhyay…·Shailja Singh

This paper investigates how replenishing NADPH can restore redox homeostasis and lysosomal function in G6PD-deficient microglia through metabolic pathway modulation.

11 citations

mousemetabolomics

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Cell BiologyBiochimica et Biophysica Acta (BBA) - Molecular Basis of DiseasePeer-reviewedJul 27, 2024

G6PD deficiency mediated impairment of iNOS and lysosomal acidification affecting phagocytotic clearance in microglia in response to SARS-CoV-2

Abir Mondal, Subrata Munan, Isha Saxena…·Soumya Pati

This study shows that G6PD deficiency in microglia impairs iNOS-mediated NO production and lysosomal acidification, leading to reduced phagocytosis of SARS-CoV-2 and increased COVID-19 severity.

10 citations

humanbulk RNA-seq

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