D. Lai

This paper develops a human heart-on-a-chip model using iPSC-derived cardiomyocytes, fibroblasts, and vascular endothelial cells, showing improved cardiac function and responses similar to in vivo hearts.

This study shows that increasing KCC2 in mice reduces seizure-like activity and prevents status epilepticus, suggesting KCC2 targeting could help treat excitation-inhibition imbalances.