Author

Yaroslav E. Abramenko

Russian Academy of SciencesORCID 0009-0005-2946-3257Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexandra V. BruteriD· 2 shared Alvina I. KhamidullinaiD· 2 shared Victor Vyacheslavovich TatarskiyiD· 2 shared Alexander Albertovich ShtiliD· 1 shared Alexander TyakhtiD· 1 shared Anastasia M. KhrustalevaiD· 1 shared Anna V. TvorogovaiD· 1 shared Chang‐Uk Lim· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Alexandra V. BruterORCID

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2 papers

Recent·Most cited

Cancer BiologyCell Death DiscoveryPeer-reviewedFeb 15, 2025

CDK8/19 Inhibition Attenuates G1 Arrest Induced by BCR-ABL Antagonists and Accelerates Death of Chronic Myelogenous Leukemia Cells

Alvina I. Khamidullina, Margarita A. Yastrebova, Alexandra V. Bruter…·Victor Vyacheslavovich Tatarskiy

This study shows that CDK8/19 inhibition overcomes BCR-ABL inhibitor-induced G1 arrest and promotes apoptosis in CML cells.

8 citations

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintJan 23, 2025

Eg5 Inhibitor SB743921 Causes p53-Dependent Cell Cycle Arrest, Senescence and Death in Tumor Cells

Yaroslav E. Abramenko, Alvina I. Khamidullina, Tamara A Kiryukhina…·Victor Vyacheslavovich Tatarskiy

This study shows that the Eg5 inhibitor SB743921 induces p53-dependent cell cycle arrest, senescence, and death in tumor cells, particularly in TP53-mutated cells, with potential for combinational therapy with senolytic drugs.

DOI 10.1101/2025.01.23.634373

humanexperimental assay

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