Author

Sai S. Chelluri

University of California, BerkeleyORCID 0009-0005-5863-203XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Bryan Castillo-RojasiD· 1 shared Elizabeth TheuschiD· 1 shared Eva HarrisiD· 1 shared Evan Y. W. JuaniD· 1 shared Felix PahmeieriD· 1 shared Marcus P. WongiD· 1 shared Neil Victor YangiD· 1 shared Phoebe Wang· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Bryan Castillo-RojasORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 1, 2025

TOMM40 Knockdown in Macrophages Inhibits Oxidized LDL-induced NLRP3 Activation and Promotes LXR-β Mediated Cholesterol Transporter Gene Expression

Sai S. Chelluri, Neil Victor Yang, Elizabeth Theusch, Ronald M. Krauss

This study shows that TOMM40 knockdown in macrophages inhibits NLRP3 activation and increases LXR-β mediated cholesterol transporter gene expression, potentially reducing atherogenesis.

DOI 10.1101/2025.07.01.662675

mousebulk RNA-seq

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ImmunologyPLoS PathogensPeer-reviewedApr 25, 2024

The Inflammasome Pathway is Activated by Dengue Virus Non-structural Protein 1 and is Protective During Dengue Virus Infection

Marcus P. Wong, Evan Y. W. Juan, Sai S. Chelluri…·Eva Harris

This study shows DENV NS1 activates inflammasomes in macrophages, leading to IL-1β release without pyroptosis, and that this pathway is protective against DENV infection.

20 citations

mousehuman

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