Author

Jim Gkantalis

Institute of Cancer ResearchORCID 0009-0006-0693-2011Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alan A. MelcheriD· 1 shared Alexis J. CombesiD· 1 shared Amy BurleyiD· 1 shared Ann LazariD· 1 shared Anton PatrikeeviD· 1 shared Antonio RullaniD· 1 shared Charleen Chan Wah HakiD· 1 shared Eleanor Clancy‐Thompson· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Alan A. MelcherORCID

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2 papers

Recent·Most cited

Cancer BiologyJournal for ImmunoTherapy of CancerPeer-reviewedMar 1, 2025

Identification of a conserved subset of cold tumors responsive to immune checkpoint blockade

Jade Moore, Jim Gkantalis, Inés Guix…·Mary Helen Barcellos‐Hoff

This study identifies a biomarker, {beta}Alt, that predicts immune checkpoint blockade response in cold tumors by integrating TGF{beta} signaling, DNA repair, and immune context signatures.

10 citations

humanmouse

𝕏 PostBluesky

ImmunologyNature CommunicationsPeer-reviewedAug 12, 2024

Sculpting the tumour microenvironment by combining radiotherapy and ATR inhibition for curative-intent anti-PD-L1- and anti-NKG2A-based adjuvant immunotherapy

Emmanuel Christian Patin, Pablo Nenclares, Charleen Chan Wah Hak…·Kevin Joseph Harrington

This study combines ATR inhibition with radiotherapy and immune checkpoint blockade to enhance antitumour immunity in HNSCC preclinical models.

22 citations

mouseproteomics

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