ImmunologyeLifePeer-reviewed
RAG1 and RAG2 Non-core Regions Are Implicated in Leukemogenesis and Off-target V(D)J Recombination in BCR-ABL1-driven B-cell Lineage Lym-phoblastic Leukemia
Xiaozhuo Yu, Wen Zhou, Xiaodong Chen…·Yanhong Ji
This study shows that non-core RAG regions reduce off-target V(D)J recombination and maintain genomic stability in BCR-ABL1+ B-ALL by improving RAG cleavage accuracy.
5 citations