Author
University of BernORCID 0009-0006-8308-5493Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Dilara Akhoundova, Martín González Fernández, Aavash Baral…·Mark A. Rubin
The paper identifies Aurora kinase A as a synthetic lethal target in FANCA-deficient cancers and shows AURKA inhibition induces chromosomal instability and G2/M arrest in these cells.
Gwendoline Hoslett, Sara Tribble, Pauline Lascaux…·Kristijan Ramadan
This study identifies nucleophagy as the mechanism by which trapped PARP1 is cleared, showing that inhibiting this process re-sensitizes PARPi-resistant cells to PARPi.
Lea Lingg, Merve Mutlu, Arunasalam Naguleswaran…·Paola Francica
This study identifies TAOK1 as a regulator of replication fork stability in BRCA1/2-deficient tumors, showing it enhances sensitivity to PARPi and IR through PCNA and ISG15 interactions.
Marina Maurizio, María Masid, Kerry L. Woods…·Philipp Olias
The paper identifies host metabolic pathways essential for malaria and related hemoparasites by combining a metabolic model and CRISPR screen.
Natalia Colás-Algora, Pablo Muñoz-Pinillos, Susana Barroso…·Jaime Millán
The paper shows that activating RhoC at cell junctions preserves endothelial barrier function during inflammation by enhancing adherens junctions and stabilizing actomyosin.