Yasumasa Ishida

This study identifies Zbtb38 as a transcriptional activator of XIAP, showing its role in regulating apoptosis during development and cancer, with implications for therapeutic targeting.

This study shows that PD-1 knockout mice with genome mutations develop liver granulomatous inflammation, supporting PD-1's role in suppressing autoimmune responses to neoantigens.

This study shows that overexpressing an allogeneic MHC-I molecule on tumor cells can induce anti-tumor immunity in PD-1 knockout mice, even without PD-1 signaling.

This study shows that heterozygous ZBTB38 loss in mice causes early embryonic lethality by reducing Nanog and Sox2 expression, while ZBTB38 is not essential for ES cell establishment.