Natasha S. Kelkar

This study characterizes PUB33, an Arabidopsis RLCK-IXb/PUB-VI protein, showing it has dual kinase and E3 ubiquitin ligase activities regulated by autophosphorylation and interacts with the bacterial effector RipV1 to modulate immune responses.

The study shows engineered antibodies lacking Fc receptor binding improve HSV protection, suggesting vaccine strategies targeting IgG3 could enhance immunity.

The paper identifies a humoral correlate of protection against tuberculosis in humans and non-human primates, showing cross-species and vaccine regimen consistency.

This study compares complement-mediated immunity differences between humans and rhesus macaques, finding sex-based variations in humans and species-specific differences in complement activity.

This study shows that both neutralization and effector functions of antibodies are needed for effective protection against neonatal HSV-1, while effector functions alone suffice for HSV-2.