Paula Ramiro-Martínez

This study identifies multireplicon plasmids in bacterial genomes, showing they are common, gene-rich, and shaped by predictable fusion rules that influence AMR spread.

The paper shows plasmid mutation rates increase logarithmically with copy number, outpacing segregational drift, enhancing bacterial evolvability.

The paper analyzes plasmid copy numbers across bacterial species and identifies a universal scaling law linking copy number and plasmid size.

This study shows that β-lactamase expression in E. coli induces collateral sensitivity to colistin and azithromycin, suggesting a therapeutic strategy to counter mobile AMR.