Author

Seongok Kim

Tufts UniversityORCID 0009-0007-7313-5386Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 1

Frequent Co-Authors

Mengyun ZhangiD· 2 shared Ralph R. IsbergiD· 2 shared Albert TaiiD· 1 shared Atish Roy ChowdhuryiD· 1 shared Kristin M. Kotewicz· 1 shared Meghan S. MartiniD· 1 shared Rebecca A. ScheckiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

Mengyun ZhangORCID

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2 papers

Recent·Most cited

MicrobiologyNature CommunicationsPeer-reviewedAug 30, 2024

Sde Proteins Coordinate Ubiquitin Utilization and Phosphoribosylation to Promote Establishment and Maintenance of the Legionella Replication Vacuole

Kristin M. Kotewicz, Mengyun Zhang, Seongok Kim…·Ralph R. Isberg

This study shows Sde proteins in Legionella pneumophila use deubiquitination and phosphoribosylation to manipulate host ER structure and evade autophagy.

20 citationstop 3%

humanproteomics

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MicrobiologybioRxivPreprintJun 27, 2023

The Sde phosphoribosyl-linked ubiquitin transferases exploit reticulons to protect the integrity of the Legionella-containing vacuole

Mengyun Zhang, Seongok Kim, Ralph R. Isberg

This study shows that Legionella pneumophila uses Sde proteins to modify Rtn4, forming ER aggregates that protect the Legionella-containing vacuole from host disruption.

DOI 10.1101/2023.06.27.546723

humanexperimental assay

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