Jiafeng Li

This study shows that chronic liver fibrosis leads to systemic CD8+ T cell hyperfunction, impairing tumor control and immune response.

The paper constructs a pan-cancer co-expression network integrating RNA and protein data to identify immune-related pathways and prognostic modules across cancers.

This study examines gene expression changes in CD8 T cells from HCV-infected individuals with varying fibrosis stages, identifying lasting hyperfunction and upregulated Hedgehog signaling in cirrhosis.