Author
University of BristolORCID 0009-0008-1268-1217Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Lorenzo Tulli, Alessio Lodola, Adrian John Mulholland, A. Sofia F. Oliveira
This study uses D-NEMD simulations to show how cancer mutations in EGFR alter allosteric communication networks and signal propagation within the kinase domain.
A. Sofia F. Oliveira, Lorenzo Tulli, Fiona L. Kearns…·Adrian John Mulholland
This study uses D-NEMD simulations to show how pH changes induce variant-specific conformational changes in SARS-CoV-2 spike proteins, affecting their stability and entry mechanisms.
A. Sofia F. Oliveira, Fiona L. Kearns, Mia A. Rosenfeld…·Adrian John Mulholland
This paper uses D-NEMD simulations to study how the fatty acid site in the glycosylated SARS-CoV-2 spike modulates its structure and function, revealing allosteric networks and the role of glycans.