BiochemistrybioRxivPreprint
Cancer-associated mutations reconfigure dynamical responses in EGFR kinase
Lorenzo Tulli, Alessio Lodola, Adrian John Mulholland, A. Sofia F. Oliveira
This study uses D-NEMD simulations to show how cancer mutations in EGFR alter allosteric communication networks and signal propagation within the kinase domain.
DOI 10.64898/2026.10.08.757680