Author

Gahyun Lee

Stony Brook UniversityORCID 0009-0008-1464-1809Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:ChIP-seq· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

Dongyan TaniD· 2 shared Vladyslava SokolovaiD· 2 shared A. M. MullinsiD· 1 shared Abhishek SingharoyiD· 1 shared Bang Hua Pan· 1 shared Evgeny NudleriD· 1 shared Jacob Miratsky· 1 shared John VantiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Dongyan TanORCID

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2 papers

Recent·Most cited

BiochemistryCommunications BiologyPeer-reviewedOct 8, 2026

MacroH2A-Mediated Gene Repression through Nucleosome Compaction and Remodeling Inhibition

Vladyslava Sokolova, Rulan Jiang, A. M. Mullins…·Dongyan Tan

This study investigates how MacroH2A (mH2A) contributes to gene repression by stabilizing nucleosome dynamics and inhibiting chromatin remodelers.

DOI 10.1038/s42003-026-10969-4

ChIP-seqexperimental assay

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BiochemistryStructurePeer-reviewedOct 8, 2024

Structural mechanism of HP1-dependent transcriptional repression and chromatin compaction

Vladyslava Sokolova, Jacob Miratsky, Vladimir V. Svetlov…·Dongyan Tan

This study determines the cryo-EM structure of HP1 bound to an H2A.Z nucleosome, revealing two binding sites and their roles in transcriptional repression and chromatin compaction.

13 citations

humanstructural biology

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