BiochemistryNature CommunicationsPeer-reviewed
Activation and substrate specificity of the human P4-ATPase ATP8B1
Thibaud Dieudonné, Felix Kümmerer, Michelle Juknaviciute Laursen…·Poul Nissen
This study presents cryo-EM structures and functional analysis of the human ATP8B1-CDC50A complex, revealing its mechanism of action, substrate specificity, and regulation by phosphoinositides.