Rumen Stamatov

This study uses live-cell microscopy to analyze PCNA and RPA1 dynamics during replication fork stalling and restart in response to hydroxyurea, revealing distinct processes and the role of ATR in fork restart.

The paper measures ATM and MDC1 recruitment kinetics at DNA lesions and proposes activated ATM diffusion as the mechanism for MDC1 spread beyond the damage site.

This study measures the kinetics of SARS-CoV-2 virus-like particle internalization using live-cell microscopy, revealing key steps and their timing, and showing no effect of Omicron mutations or S protein cleavage site on internalization rates.

CellTool is an open-source software for image analysis and mathematical modeling, offering tools for processing time-lapse microscopy data and custom model fitting.