PhysiologyCell chemical biologyPeer-reviewed
β-hydroxybutyrate is a metabolic regulator of proteostasis in the aged and Alzheimer disease brain
Sidharth S. Madhavan, Stephanie Roa Diaz, Sawyer Peralta…·John C. Newman
This study identifies β-hydroxybutyrate as a metabolic regulator of protein solubility in aging and Alzheimer's disease, showing it reduces insolubility of pathological proteins like amyloid-β.
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