Mingyu Gan

This study shows desiccation-induced DNA damage in Mtb leads to mutations and drug resistance by affecting DNA repair and gene expression.

This study identifies idsA2 mutations as a mechanism of ethambutol resistance in Mtb by showing they enhance drug resistance through metabolic remodeling.

The paper analyzes global M. abscessus genomes to show that recently emerged clones spread across countries and show shifts in selective pressures during expansion.

The paper uses dual RNA-seq in zebrafish to study transcriptional programs in tuberculous granulomas, finding neutrophils and necrosis drive bacterial survival and adaptation.

This study identifies MHC-II antigens from Mycobacterium tuberculosis using mass spectrometry and evaluates mRNA vaccine immunogens to enhance T cell recognition.

This study examines transcriptional plasticity in Mycobacterium tuberculosis across diverse environmental conditions and identifies genetic factors influencing it.

This study shows that mycobacterial DnaQ acts as an alternative proofreader, working with the PHP domain to maintain DNA replication fidelity and prevent mutations.