Cancer BiologybioRxiv
TPX2 expression promotes sensitivity to dasatinib in breast cancer by activating the YAP transcriptional signaling.
Carlos Marugán, Natalia Sanz‐Gómez, Beatriz Ortigosa…·Guillermo de Cárcer
The paper identifies TPX2 as a gene that increases breast cancer sensitivity to dasatinib by activating the YAP pathway, and shows TPX2 and YAP are biomarkers for poor prognosis and potential dasatinib therapy.
DOI 10.1002/1878-0261.13602