Author

Bryan Hsu

Broad Institute of MIT and HarvardORCID 0009-0009-7541-1203Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Al OzonoffiD· 1 shared Arjun Chandran· 1 shared Cassandra Areff· 1 shared Colby Wilkason· 1 shared Daphne YangiD· 1 shared Daven LimiD· 1 shared Dora Nabatanzi· 1 shared Elyse StachleriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Al OzonoffORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintNov 12, 2026

Direct Whole-Blood PCR for Molecular Diagnostics

Jongwon Lim, Elyse Stachler, Stella Nielsen…·Pardis Sabeti

This paper develops an extraction-free qPCR workflow for direct whole-blood testing of viral pathogens, achieving detection limits of 10 copies/uL for DNA and 100 copies/uL for RNA in spiked blood samples.

DOI 10.64898/2026.11.10.765582

bulk RNA-seqexperimental assay

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BioinformaticsbioRxivPreprintMay 15, 2025

Interpreting biochemical text with language models:a machine learning framework for reaction extraction and cheminformatic validation

Daven Lim, Swathi Badrinarayanan, Kira Sterling…·J. Christopher Anderson

This paper presents a framework using LLMs and cheminformatics to extract and validate enzymatic reactions from scientific text, showing accurate inference of incomplete reactions.

2 citations

machine learning (classical)benchmarking

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