Sofia Dahlman

This study identifies and characterizes prophage induction mechanisms in gut bacteria, showing that DNA damage reliably triggers induction of prophages encoding CI-like repressors.

The paper identifies pre-existing anti-prophage antibodies and bacterial heteroresistance as factors contributing to phage therapy failure in a patient with chronic infection.

The paper characterizes active temperate gut phages from bacterial isolates, finding most are inactive and their induction is complex and context-dependent.