Samuel C. Forster

This paper shows that the rabies virus P protein selectively inhibits certain IFN-stimulated and repressed genes while allowing others, demonstrating that IFN-antagonists can modulate specific pathways rather than globally suppressing IFN signaling.

This study identifies and characterizes prophage induction mechanisms in gut bacteria, showing that DNA damage reliably triggers induction of prophages encoding CI-like repressors.

The paper identifies metabolically flexible fermenters as drivers of increased intestinal gas production in Crohn's disease by analyzing microbial genomes and metagenomes.

This study identifies the group B [FeFe]-hydrogenase as the primary enzyme driving fermentative H2 production in the human gut, linking it to gut health and disease.

The paper characterizes active temperate gut phages from bacterial isolates, finding most are inactive and their induction is complex and context-dependent.

This study shows that fecal microbial transfer and complex carbohydrates can reduce COPD symptoms in mice and humans, linking gut microbiota to disease progression.

The paper demonstrates broad host range mobile genetic elements transferring antibiotic resistance from human gut commensals to enteropathogens.

CiiiDER predicts and analyses transcription factor binding sites using experimentally verified motifs, offering enrichment analysis to identify regulatory pathways.