Simulation of enteric colonisation by and screening for Carbapenemase Producing Enterobacteriaceae using an in-vitro human gut model.

Introduction Introduction Methods Results Discussion Conclusion Appendix 1 Appendix 2 References Carbapenemase Producing Enterobacteriaceae (CPE) are increasing worldwide [1, 2] and pose a significant threat to public health. The burden of CPE infection is multifaceted, encompassing adjustment of treatment regimens [3, 4], increased duration of inpatient stay [5], associated morbidity [6] and mortality [5, 7, 8], in addition to the wider burden it poses on healthcare systems, with financial and societal implications [9]. The rapid spread of CPE within endemic areas [10] and in ...