E. Clark

The ANKS3/BICC1 protein complex is a master post-transcriptional regulator of NPHP1 ciliopathy gene transcripts

The paper identifies ANKS3/BICC1 as a post-transcriptional regulator of NPHP1 transcripts, linking it to ciliopathy phenotypes through transcript decay and ciliary dysfunction.

Flexible and scalable control of T cell memory by a reversible epigenetic switch

The paper identifies a reversible epigenetic switch in T cells that controls memory potential, allowing flexible responses to pathogen virulence.

Overabundance of Asaia and Serratia bacteria is associated with deltamethrin insecticide susceptibiltiy in Anopheles coluzzii from Agboville, Cote d'Ivoire

The paper identifies associations between deltamethrin resistance in Anopheles coluzzii and specific bacterial genera, suggesting potential microbial markers for insecticide resistance surveillance.

Pilot study: Trehalose-induced remodelling of the human microbiota affects Clostridioides difficile infection outcome in an in vitro colonic model

This study shows that trehalose supplementation remodels the human gut microbiota, preventing simulated Clostridioides difficile infection in an in vitro model.

Heme is crucial for medium-dependent metronidazole resistance in clinical isolates of C. difficile

The paper shows heme dependence in metronidazole resistance in C. difficile clinical isolates, linked to a SNP in hsmA and associated with a resistant lineage.

Profiling the effects of rifaximin on the healthy human colonic microbiota using a chemostat model

This study evaluates three rifaximin formulations on the human colonic microbiota using chemostat models, finding that formulation {kappa} caused the least disruption.

Simulation of enteric colonisation by and screening for Carbapenemase Producing Enterobacteriaceae using an in-vitro human gut model.

The paper simulates enteric colonization by Carbapenemase Producing Enterobacteriaceae (CPE) using an in-vitro human gut model and screens for CPE.