metagenomics
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- BioinformaticsbioRxivPreprintDOI 10.64898/2026.11.09.765303
- MicrobiologybioRxivPreprint
Integrating Microbial Ecology and Sustainability: Linking Agricultural Waste Gas Streams to Microbial Community Shifts in a Photobioreactor
Marta Velaz Martin, Till Glockow, Laura Meisch…·Christof M Niemeyer
This study examines microbial community dynamics in a photobioreactor using agricultural waste gas streams, showing spatially structured communities and partial nitrogen recovery.
DOI 10.64898/2026.11.06.764810 - BioengineeringbioRxivPreprint
Material context and TGF-β blockade timing determine retained matrix in patient-derived bioprinted keratoconus stroma
Hanyu Jiang, Chang Zhou, Fei Gao…·Yang Jiang
This study shows that timing of TGF-β blockade and material context affect matrix retention in bioprinted keratoconus stroma, with optimal regimens improving collagen retention and reducing contractile gene expression.
DOI 10.64898/2026.11.04.764220 - BiochemistrybioRxivPreprint
A Minimal Synthetic Cleavage Module Enables Selective Degradation of Pathogenic r(CUG) Repeats in Cells
Jingsong Shan, Sandra Kovachka, Kisu Sung, Matthew David Disney
This study develops a synthetic cleavage module that selectively degrades pathogenic r(CUG) repeats in cells, reducing DM1-associated pathology without DNA damage.
- BioinformaticsbioRxivPreprint
Application of metagenomic sequencing to improve sessile serrated lesion detection using the faecal immunochemical test
Bradley J Hart, Geraldine Laven-Law, Clarice M Harker…·Michael J Roach
This study investigates whether FIT samples can reveal a microbial signature of sessile serrated lesions, finding no significant differences in community structure but suggesting potential functional differences.
DOI 10.64898/2026.11.04.764411 - BioinformaticsbioRxivPreprint
Contrastive Learning Improves Generalization on M2OR Olfactory Binding Dataset
Logan Snider, Oliver Nakano-Baker, J. Devin Mackenzie
The paper evaluates contrastive learning on VOC-OR binding datasets, showing improved generalization and reduced performance inflation from identity leakage.
DOI 10.64898/2026.11.04.763508 - Evolutionary BiologybioRxivPreprint
A new Serratia taxon found in a trombidiform mite shows genomic evidence of host adaptation but is phylogenetically distinct from Serratia symbiotica
Jia Chang, Ary Hoffmann, Neil David Young…·Joshua A Thia
The paper identifies a new Serratia taxon in mites with genomic signs of host adaptation but phylogenetically distinct from S. symbiotica.
DOI 10.64898/2026.11.03.764106 - GenomicsbioRxivPreprint
Unprecedented urban freshwater microviral survey highlights shift from sewage to river water communities
Alisa Langlais, Celtill Dumont, Jeremy Mougin…·Achim Quaiser
The paper surveys microviruses in urban freshwater environments, finding shifts in community composition from sewage to river water, with wastewater treatment plants acting as filters.
DOI 10.64898/2026.11.03.763685 - BioinformaticsbioRxivPreprint
MicrobeRT: A Framework and Suite of Fine-tuned Language Models for Genomic Sequences
Vijay Narayan, Brian Merritt, Sanjeevani Choudhery…·Molly E Gallagher
MicrobeRT is a framework of fine-tuned language models for metagenomic analysis, achieving strong performance in taxonomic classification, antibiotic resistance detection, and pathogenicity assessment.
- BioinformaticsbioRxivPreprint
Sourmash accurately profiles strains from long-read metagenomes preserving gene content
Lune Angevin, Josipa Lipovac, Pierre Peterlongo…·Riccardo Vicedomini
This study evaluates Sourmash's ability to profile microbial strains from long-read metagenomes, showing accurate gene content recovery and abundance estimation.
DOI 10.64898/2026.11.03.763925 - Plant BiologybioRxivPreprint
Effects of Reduced Watering Regimes on Hops Growth and Rhizospheric Microbial Communities
Alexandra McElwee-Adame, Caden Mulligan, Kailyn Kibury…·Arun Sethuraman
This study examines how reduced watering affects hops growth and rhizospheric microbial communities across five cultivars, finding differential plant responses and consistent microbial associations with cultivar type.
DOI 10.64898/2026.11.03.764026 - BioinformaticsbioRxivPreprint
Phylogeny-Guided Global-Local Shrinkage for Microbiome Feature Selection
Zihan Zhu, Shuangjie Zhang, Xueying Tang, Liangliang Zhang
This paper introduces PGL, a Bayesian regression method for microbiome feature selection that uses phylogenetic trees to improve detection of exposure-associated ASVs.
DOI 10.64898/2026.10.28.762580 - EcologybioRxivPreprint
Individual-specific recovery of the healthy human gut microbiota after antibiotics
Shaya Kahn, Jonathan Friedman, Amir Bashan
The paper shows that the human gut microbiota recovers to an individual-specific state after antibiotics, not to a generic healthy state.
DOI 10.64898/2026.10.30.762915 - MicrobiologyiSciencePeer-reviewed
Farm exposure is associated with human breast milk immune profile and microbiome
Mary Hannah Swaney, Olivia Steidl, Anastasia Tackett…·Anne Marie Singh
The paper compares immune profiles and microbiomes of breast milk from mothers with different farm exposures to identify associations with immune development and atopic disease.
2 citations - BioinformaticsbioRxivPreprint
Interpreting graph neural networks reveals microbial association patterns in inflammatory bowel diseases
Andre Ferreira Cunha, Edir Vidal, María Barranco-Altirriba…·Alberto Santos
The paper uses graph neural networks to interpret microbial association patterns in IBD, showing that coordinated associations, not just abundance shifts, are predictive.
DOI 10.64898/2026.10.27.762128 - EcologybioRxivPreprint
Host specificity, seasonality, and urbanicity shape the gut microbiome of a synanthropic insect
Hanna Noyes, Nur-E-Jannat Anika, Julia Combs…·David R. Angelini
This study examines how host plant, season, and urbanization affect the gut microbiome of soapberry bugs, finding that host plant is the primary driver of microbial community structure.
DOI 10.64898/2026.10.28.762591 - EcologybioRxivPreprint
Differing patterns in community composition and diversity of biofilm-forming bacteria and fungi along a large salinity gradient
Leena Virta, Jianjun Wang, Iines S. Salonen
The paper examines how bacterial and fungal biofilm communities respond to salinity gradients, finding distinct patterns in diversity and environmental drivers between the two groups.
DOI 10.64898/2026.10.28.762137 - MicrobiologybioRxivPreprint
Stream and lake network position structures freshwater microbial communities across multiple catchments
Anish A. Kirtane, Kristy Deiner, Alex R. Hall
The paper shows bacterial community composition changes consistently across hydrological network positions in freshwater systems.
DOI 10.64898/2026.10.29.762755 - MicrobiologybioRxivPreprint
Temporal Dynamics Outweigh Fungicide Treatment in Shaping the Turfgrass Phyllosphere Resistome
Natalie R. Wieber, Sara G. Haney, James Lazarcik…·Jeri D. Barak
This study shows that temporal changes in the phyllosphere microbiome have a greater impact on antibiotic resistance gene abundance than fungicide treatment.
DOI 10.64898/2026.06.02.729574 - ImmunologyiSciencePeer-reviewed
ESX-5 Deletions in Mycobacterium tuberculosis Alter Macrophage Cytokine Signaling and Bacterial Heavy Metal Response
Austin M. Haynes, Sara Beth Cohen, Aparajita Pesaladinne…·Thomas R. Hawn
This study shows that ESX-5 deletions in Mtb reduce cytokine secretion in macrophages via a post-transcriptional mechanism and alter heavy metal response genes.
- MicrobiologybioRxivPreprint
Population-scale dietary signatures of the oral microbiome
Kaiyu Liang, Haochen Xue, Anastasia Godneva…·Imran Razzak
The paper examines diet-oral microbiome associations using metagenomic data from 5,824 participants, finding shared microbial signatures across dietary patterns.
DOI 10.64898/2026.10.28.762516 - MicrobiologybioRxivPreprint
AP2-L-Dependent Processes Promote PVM Maintenance and Plasmodium Liver-stage Development
Destaalem T. Kidane, Anusha Thaniana, Farhana Mosaddeque…·Purnima Bhanot
This study shows AP2-L is essential for Plasmodium liver-stage development by regulating PVM formation and host-cell interactions.
DOI 10.64898/2026.10.29.762720 - Genomicsnpj Antimicrobials and ResistancePeer-reviewed
Antimicrobial use contributes to resistance gene enrichment across cattle groups on commercial dairy farms
Andrew J. Steinberger, Colette A. Nickodem, Juliana Leite de Campos…·Jessica L. Hite
The paper links antimicrobial use (AMU) on dairy farms to variations in resistance gene profiles across cattle groups, showing that higher AMU correlates with increased resistance to certain drug classes.
DOI 10.1038/s44259-026-00291-8 - MicrobiologybioRxivPreprint
Comparisons among Yanomami populations reveal transitional gut microbiome configurations under urban influence
Lucas Amoroso Lopes de Carvalho, Marie Thorp, Maarten Ciers…·Luciana Campos Paulino
The paper compares gut microbiomes of Yanomami populations with varying urban influence and a Belgian urban cohort, finding urban-associated features and shifts in microbial composition and function.
DOI 10.64898/2026.10.27.762328 - BioinformaticsbioRxivPreprint
Perturbation-based propagation of bacterial composition uncertainty improves robustness and reproducibility of microbiome differential abundance analysis.
Madison E Andrews, Tessa Vincennie, Milica Koprivica…·Benoit Mouzon
PARALLAX improves microbiome differential abundance analysis by addressing compositional data, uncertainty, and experimental design through a unified framework with stability-based metrics.
DOI 10.64898/2026.10.23.760456 - ImmunologybioRxivPreprint
Early tuberculosis treatment remodels blood mRNA and small RNA, and a baseline host signature is associated with early culture conversion
G. V. Anoushka Chinmayi, Darla Quijada, Artur T. L. Queiroz…·Petros C. Karakousis
This study identifies blood-based biomarkers that predict early tuberculosis culture conversion by analyzing mRNA and small RNA changes during treatment.
DOI 10.64898/2026.10.25.761687 - MicrobiologyMicrobial EcologyPeer-reviewed
CULTURE AND ISOLATION OF BACTERIA ASSOCIATED WITH MEDITERRANEAN CORALS
Rocio Mozo, Andrea Illa-Oviedo, Javier del Campo
The paper isolates and cultures bacteria from four Mediterranean corals, identifying 84 pure isolates, including novel species, to better understand their roles in the coral holobiont.
DOI 10.1007/s00248-026-02919-8 - MicrobiologyMicrobiology SpectrumPeer-reviewed
Integrated microbiome and metabolomic profiling reveals alterations across the adenoma-colorectal cancer sequence
Tien-En Chang, Hung‐Hsin Lin, Jiing–Chyuan Luo…·Ming‐Chih Hou
This study identifies microbial and metabolic changes across the adenoma-carcinoma sequence in colorectal cancer using 16S rRNA sequencing and metabolomic profiling.
DOI 10.1128/spectrum.01059-26 - NeurosciencebioRxivPreprint
Understanding cognitive function in post-COVID-19 condition with fatigue: an interdisciplinary multimodal investigation
Ulrika Birberg Thornberg, Anders Eklund, Kristin Zeiler…·Ida Blystad
This study investigates cognitive symptoms in post-COVID-19 condition with fatigue, finding subtle neurobiological changes not captured by standard assessments.
- MicrobiologybioRxivPreprint
There are cores, indicators, and differences - a high-throughput and quantitative PCR study of the Ambrosia artemisiifolia L. leaf, root, and seed endophytic bacterial microbiomes within the European invasive range
Tomasz Grzyb, Michal Hrabovský, Barbara Tokarska‐Guzik, Justyna Szulc
The paper profiles endophytic bacterial microbiomes in Ambrosia artemisiifolia L. tissues across Europe, finding tissue type shapes community structure more than region or habitat.
DOI 10.64898/2026.10.23.761399