Advanced MRI Techniques and Applications

This study evaluates a new MRI method using simulations to measure full CSF dynamics in the brain, showing it can accurately separate motion components despite model assumptions.

This study uses high-resolution MRI to map glymphatic transport in deep brain regions by directly infusing Gd into the lateral ventricle and analyzing PVS signal enhancements.

ProFit-1D was adapted to fit J-difference edited spectra at 3T and showed higher accuracy and precision than existing software for estimating metabolite concentrations.

This paper demonstrates direct in vivo collagen imaging using MRI with microsecond echo times, enabling collagen-specific depiction through echo subtraction.

This paper develops a fast method to quantify cerebral metabolites using 2D 1H-MRSI with a quantitative MRI-based water reference, showing improved accuracy over traditional methods.

This paper introduces Romer-EPTI, a novel dMRI technique that improves SNR, motion robustness, and image quality for in-vivo mesoscale imaging.

This study examines macrovascular and microvascular coupling in adolescents using 4D flow MRI and BOLD reactivity, finding age-related changes in cerebrovascular responses.

The paper demonstrates that optimizing MP2RAGE sequence parameters for B1+-inhomogeneity tolerance can be combined with a 2D look-up-table approach to accurately estimate R1-maps without additional B1+-maps.

This paper develops a high-resolution pCASL imaging setup for rodents, improving spatial resolution and enabling better delineation of brain areas in health and disease.

This paper identifies and corrects a novel artifact in multiband fMRI data using MARSS, improving signal-to-noise ratio and reducing systematic spatial patterns.

The paper investigates age-related changes in metabolite T2 relaxation times across the adult lifespan in a multi-site cohort, finding significant declines in several metabolites with aging.

This study evaluates ultrafast Z-spectroscopy MRI with pH correction for measuring mitochondrial oxidative phosphorylation in human skeletal muscle.

This paper introduces single-shot Echo Planar Time-resolved Imaging (ss-EPTI) to improve motion robustness, temporal resolution, and SNR efficiency in dynamic imaging applications.

The paper develops a 128-channel receive array for 10.5T brain imaging, showing SNR gains and plateau effects in central regions.

The paper identifies a spatiotemporal pattern of cerebral blood flow in infants that correlates with cortical specialization and developmental functioning.

This study evaluates hemodynamic models of the BOLD response across the adult lifespan, finding that three-parameter models and biophysical models like HDM capture age-related changes effectively.

The paper presents a model-driven meta-analysis showing inhibitory neurons dominate BOLD-fMRI responses, with excitatory neurons contributing less than 20%.

This paper introduces ASEME-EPI, a new fMRI sequence combining GRE and SE to improve BOLD contrast-to-noise ratio and specificity in high-field preclinical imaging.

This study uses combined PET/MR imaging to show that visual stimulation in humans increases glucose metabolism more than oxygen consumption in visual regions, while other cortical areas show oxidative downregulation.

This study assesses how defacing structural MRI images affects quality assessments by humans and automated tools, finding significant human bias and minimal impact on MRIQC metrics.

This study evaluates inter- and intra-rater variability in quality scoring of fetal brain MRI reconstructions across three pipelines and identifies systematic weaknesses in the methods.

This study examines cardiovascular and vasomotor pulsations in the brain and periphery during awake and NREM sleep using fMRI and photoplethysmography, finding increased synchrony and power in vasomotor waves during sleep.

The paper describes a postmortem MRI protocol for the Douglas-Bell Canada Brain Bank to acquire high-resolution images while preserving tissue for histological analysis.

This paper introduces a novel 2D J-resolved metabolite-cycled semiLASER spectroscopy method to quantify 16 metabolites in the human brain at 9.4 T, demonstrating improved sensitivity and reduced acquisition time.

This paper develops a water relaxation atlas to correct metabolite concentrations in MRS by integrating age and region-specific relaxation values into the analysis workflow.

The paper assesses consistency of rat fMRI results across 12 centers using a unified pipeline and identifies variability due to experimental differences.

This paper introduces a novel fMRI scheme that simultaneously acquires reversed phase-encoding EPI data in a single session, reducing acquisition time and energy deposition while evaluating distortion correction's impact on submillimetre fMRI.

DeepResBat improves MRI data harmonization by addressing covariate distribution differences, outperforming existing methods while avoiding false associations.

The paper examines how transdiagnostic symptom domains relate to head motion in children during multimodal neuroimaging.

This study quantifies creatine kinase kinetics in mouse brain using 31P-MRS at 7 Tesla, showing that reduced breathing rate increases the forward rate constant by 36%.