Topic · Molecular Biology · Biochemistry, Genetics and Molecular Biology
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
154 papers
This study develops a mathematical model to predict how FGF and VEGF interact to activate MAPK signaling, finding that FGF dominates ERK phosphorylation.
Zhen Jiang, Teri Evans, Aaron M. Savage…·Robert N. Wilkinson
The paper investigates the roles of foxc1a and foxc1b in regulating angiogenesis from arteries and veins in zebrafish by modulating VEGF and Dll4/Notch signaling.
Silvia Parajes, Sophie Ramas, Didier Y. R. Stainier
This study shows that excess estrogen signaling during development causes vascular malformations in zebrafish by disrupting Hh/Vegf/Notch signaling and promoting aberrant endothelial cell behavior.
This study constructs a systems biology model to investigate how tumor receptor heterogeneity affects responses to combination anti-angiogenic therapy in cancer patients.