Neurobiology and Insect Physiology Research

The paper shows that exposure to ethyl butyrate during a critical period in Drosophila leads to long-term suppression of Or42a OSN odor responses and selective glial pruning of their axon terminals.

This study identifies a female-specific role for Nab2 in regulating insulin signaling and fat storage through neuronal control of dilp2 and dilp5 mRNA levels in Drosophila.

This paper characterizes the functional logic of Drosophila's early olfactory system, identifying how it processes odorant information into a time and rank-based representation for classification.

This study shows that dopaminergic neurons in Drosophila encode steering signals in both allocentric and egocentric coordinates during goal-directed navigation.

This study investigates how social experience alters transcriptional and chromatin states in Drosophila brains through pheromone circuits and transcription factors.

This study shows that Manduca sexta caterpillars detect airborne sound directly, not through substrate vibrations, by measuring behavioral responses to pure-tone stimuli at 150 Hz and 2000 Hz.

The paper identifies convergent gene losses and expression changes associated with blood-feeding loss in non-blood-feeding mosquitoes.

The paper characterizes neuropeptide T2A-GAL4 knock-in lines in Drosophila, showing that adult GAL4 reporter patterns may not reflect ongoing activity and can have developmental effects.

This study shows bumble bees make decisions based on uncertainty, adjusting choices to avoid errors and seeking information when uncertain, suggesting ancient neural mechanisms for uncertainty monitoring.

This study identifies excessive RAS/MAPK pathway activation as a cause of adult-onset motor axonal degeneration in Drosophila, showing that inhibiting the pathway can rescue neurodegenerative phenotypes.

This study shows that allowing honey bees to move their antennae during odor learning enhances neural processing and plasticity in the antennal lobes.

This study shows that bumblebee dorsal ocelli regulate the luminance-dependent scaling of visual system activity, affecting orientation and flight speed under different light conditions.

Four connectome-defined Drosophila NPF cell types sit in separate circuits with distinct, sometimes opposing functions; population-wide NPF knockdown hides these, and activity manipulation can differ from peptide loss.

This study investigates the role of P2 neurons in post-mating behavioral changes in Drosophila melanogaster and finds they are not responsible for altered sleep and food consumption after mating.

This study shows that insulin receptor signaling in sweet gustatory receptor neurons of Drosophila modulates sugar taste sensitivity and feeding behavior based on metabolic state.

This study investigates how mechanosensory feedback from legs coordinates the transition from flight to landing in fruit flies, showing that leg contact triggers specific behavioral and neural responses.

Seven high-speed cameras, a hybrid 2D/3D network and body-model inverse kinematics track 50 keypoints on freely moving flies; height and speed peak together at all running speeds.

This study develops a biophysical model of the antennal lobe to show how internal dynamics generate diverse mechanosensory response patterns and how these patterns change with stimulus intensity.

The paper introduces QINT, a temperature-controlled gene expression system that enables temporal regulation of gene expression in Drosophila and other organisms.

The paper investigates how dopamine and octopamine opposingly affect odor-driven neural activity and behavior in an insect olfactory circuit.

The paper shows that exposure to pathogen-associated odors in parasitoid wasps induces inherited olfactory avoidance in their offspring.

This study shows how Drosophila sechellia evolved a specialized olfactory receptor to detect ripe noni fruit, enabling temporal niche partitioning by reducing competition and parasitization.

This study assesses adult structural plasticity in Drosophila neurons by examining remodeling processes and introducing a tool to measure complexity without observer bias.

This study investigates sexually dimorphic visual processing in Aedes aegypti mosquitoes, finding that females pursue moving targets while males suppress approach behavior despite similar biomechanical capabilities.

This study identifies sex-specific neural circuits involving Nlg3, MB, and fruP1 neurons that regulate social spacing in Drosophila.

The paper identifies structured connectivity patterns in Drosophila mushroom bodies across multiple connectomes, showing reproducible pathways that prioritize food-related sensory information.

This paper presents a dynamical circuit model of C. elegans chemotaxis that captures sharp turning behavior through emergent dynamics.

The paper identifies an excitatory-inhibitory neural motif in Drosophila larvae that generates rhythmic locomotion through connectomic and simulation analyses.

This study identifies region-specific mechanosensory processes in Drosophila larvae that mediate self-righting behavior, showing Hox gene regulation is critical for this function.