Richard Benton

The paper identifies genes involved in octanoic acid resistance by combining experimental evolution and CRISPR screens in Drosophila species.

This study shows how Drosophila sechellia evolved a specialized olfactory receptor to detect ripe noni fruit, enabling temporal niche partitioning by reducing competition and parasitization.

The paper compares laboratory and wild Drosophila sechellia to assess if lab strains retain specialization phenotypes from their natural environment.

This study identifies new candidate genes and tissues associated with resistance to a natural toxin in Drosophila species through genome-wide association and transcriptome analyses.

The paper identifies a GPCR signaling pathway in Drosophila that modulates olfactory tuning properties in insect odor detection.

The paper completes and integrates data on the Drosophila olfactory system, revealing new neuron classes and relationships between sensory pathways.

This study compares single-cell transcriptomes of central brains across three Drosophila species to identify conserved and divergent features linked to ecological specialization.

The paper compares olfactory projection neuron rewiring in Drosophila sechellia and Drosophila melanogaster to show how central brain wiring changes support ecological specialization.

The paper studies the Drosophila olfactory system to show how multiple regulatory layers ensure functional precision and allow evolutionary changes in sensory neuron specification.

The paper compares connectivity patterns in the Drosophila mushroom body across species to show how evolutionary changes in neuronal connectivity relate to chemical ecology.

The paper shows that expanded sensory neuron populations in Drosophila enhance odor tracking without increasing projection neuron sensitivity.

This paper develops a method to activate specific neurons in the mammalian brain using peripheral administration of ligand precursors, demonstrating its effectiveness in inducing neurotransmitter release and behavioral responses.

The paper identifies a support cell-expressed protein, Osi8, essential for pheromone sensing in Drosophila by analyzing transcriptomic data of olfactory subsystems.

The paper investigates the evolution of olfactory receptor specificity in Drosophila by analyzing extant and ancestral IR receptors, identifying a common hotspot that influences ligand binding and functional transitions.

The paper identifies receptor gene-dependent mechanisms that ensure singular expression of olfactory receptors in Drosophila through transcriptional and post-transcriptional repression.

The paper uses Targeted DamID to profile rare Drosophila sensory neurons, identifying transcription factors and guidance molecules involved in neuron fate and wiring.

This study shows that activating locus coeruleus norepinephrine neurons enhances aversive memory retrieval in mice.

The paper identifies two male-specific pheromones in Drosophila mojavensis subspecies and shows how they contribute to sexual isolation through conserved sensory pathways and differential interpretation.

The paper shows that inhibiting programmed cell death in Drosophila olfactory neurons generates functional 'undead' neurons that integrate into circuits and contribute to evolutionary differences in carbon dioxide sensing.

This study identifies molecular and neuronal changes underlying behavioural divergence in Drosophila sechellia through mutational analysis and calcium imaging.

This paper reports the genome and transcriptome of the miniature parasitoid wasp Megaphragma amalphitanum, finding that its genome size and gene content are comparable to other chalcid wasps, despite its extreme miniaturization.

This study investigates the role of the co-receptor's ligand-binding domain in the assembly and trafficking of olfactory Ionotropic Receptors, revealing its importance in endoplasmic reticulum exit.

The paper maps sensory neuron lineages in Drosophila olfactory system and identifies Pointed's role in determining cell fates through genetic and transcriptomic analysis.

The paper identifies a molecular basis for carbonation detection using Drosophila IRs, showing that Ir56d, along with co-receptors, is essential for carbonation and fatty acid sensing.

The paper introduces FlyLimbTracker, a method for semi-automatically tracking leg segments in unmarked Drosophila, showing robustness across video resolutions and behaviors.

The paper introduces second-generation chemical labeling reagents for Drosophila that improve sensitivity and versatility while maintaining speed compared to first-generation tools.

The paper identifies IR93a as a key receptor involved in both thermosensation and hygrosensation in Drosophila, showing it functions with different partners in distinct sensory pathways.

This study identifies IR21a and IR25a as ionotropic receptors mediating cool sensing in Drosophila larvae through thermosensitive neurons.