Integrating structural modeling and divergence dating of RNA-dependent RNA polymerases to resolve the evolutionary history of plant and fungal viruses: from sobemoviruses to sobelivirads
Jérôme Gracy, Mahan Ghafari, Gilles Labesse…·Eugénie Hébrard
This study uses deep-learning structural modeling and divergence dating to analyze RdRps from plant and fungal viruses, revealing a recent divergence of sobelivirads and suggesting cross-kingdom host shifts in their evolutionary history.