Bacterial biofilms and quorum sensing

Siderophore-Mediated Competition Between Cystic Fibrosis Pathogens Increases Virulence Factor Production

This study shows Achromobacter spp. enhance Pseudomonas aeruginosa virulence by inducing siderophore production through iron competition in CF airways.

Genomic Potential vs. Pathogenic Reality: Functional Virulence Variation in Pseudomonas aeruginosa

This study links genomic diversity to phenotypic virulence in Pseudomonas aeruginosa by analyzing multiple strains and their functional behaviors.

Proteomic Insights into Strong and Weak Biofilm Formation in Acinetobacter baumannii for Potential Therapeutic Targets

This study compares proteomic profiles of strong and weak biofilm-forming Acinetobacter baumannii isolates to identify potential therapeutic targets.

A bistable type III secretion system is primed and loaded in Pseudomonas aeruginosa hypervirulent isolates with positively selected codon changes in exsA or exsD

The paper identifies positively selected codon changes in exsA or exsD that hyperactivate the T3SS in P. aeruginosa, leading to hypervirulence through increased T3SS activity and immunopathology.

Pseudomonas aeruginosa evolves to an infection state of reduced virulence and enhanced survival during antibiotic selection in an airway tissue model

This study shows that antibiotic selection in a human airway tissue model of Pseudomonas aeruginosa leads to evolution of less virulent, tissue-preserving infections with enhanced survival.

LysM: a bacterial self-encoded peptidoglycan hydrolase as an antimicrobial and anti-biofilm agent for Gram-negative nosocomial pathogens

This paper identifies LysM, a bacterial enzyme with broad-spectrum antimicrobial and anti-biofilm activity against Gram-negative pathogens, and shows it can enhance antibiotic efficacy.

Proteomics reveal temperature-coupled cobalamin homeostasis and pathogenicity in Pseudomonas aeruginosa

This study uses proteomics to show that Pseudomonas aeruginosa adjusts its cobalamin homeostasis and pathogenicity in response to temperature changes, revealing temperature-dependent shifts in metabolic strategies.

Water Kefir as a Model for Aggregative Development of Microbial Multicellularity within a Multispecies Biofilm

This study investigates water kefir grains as a model for microbial multicellularity, revealing an emergent growth function in multispecies biofilms.