Forensic and Genetic Research

The paper proposes a simulation model and software to estimate the number of males with a matching Y-chromosome profile, addressing challenges in forensic DNA evidence evaluation.

The paper analyzes ancient DNA data from Neolithic and Chalcolithic Europe to study population dynamics and admixture patterns across different regions and time periods.

The paper addresses criticisms of a previous study on identifying individuals from whole-genome sequencing data by demonstrating the limitations of Erlich's simulation and highlighting the algorithm's use of multiple trait-based predictive models.

The paper analyzes ancient and present-day genome-wide data to show widespread Paleo-Eskimo ancestry among Na-Dene and Eskimo-Aleut language speakers and presents a model for North America's peopling.

The paper analyzes 289 genome sequences from Nilo-Saharan and Niger-Congo populations to identify population-specific selection signatures linked to disease resistance.

The paper links Neolithic Y haplotypes to autism spectrum disorder (ASD) by showing higher frequencies of low SES haplotypes in ASD fathers and a male-biased ASD ratio in related surnames.

This study shows that introgression and gene flow from ancient populations create a wave in inferred effective population size, affecting population history estimates.

The paper estimates recent African gene flow into the UK population, identifying old rare variants that suggest a 1.2% contribution approximately 400 years ago.

The paper critiques Lippert et al.'s method for re-identifying individuals from whole-genome sequencing data, highlighting its flaws in performance, methodology, and conclusions.

This study detects ancient positive selection in humans by identifying genomic regions where Neandertals and Denisovans fall outside present-day human variation, finding evidence for regulatory changes associated with human-specific traits.

FastID rapidly compares DNA forensic profiles using SNP loci, achieving fast search times on standard hardware.

This study analyzes genetic data from Zoroastrians in Iran and India to explore population structure, gene flow, and selection, revealing patterns of endogamy, admixture timing, and disease-related selection.

The paper analyzes ancient genomic data from Portugal to study genetic changes during the Neolithic to Bronze Age transition, finding limited genetic influx and correlations between ancestry and stature.

This study analyzes ancient and modern genomes from the Levant to trace genetic continuity and admixture over five millennia, finding Canaanite-related ancestry and later Eurasian influences.

The paper examines cultural similarities among the Yakut population by analyzing genetic and archaeological data from ancient and modern samples, linking them to clan structures and marriage patterns.

The paper compares ancient and modern Eurasian genomes to assess if cognitive ability variants increased during the Holocene, finding significant modern genome advantages in polygenic scores.

This study applies t-SNE to human genetic data, showing it can reveal population stratification at different scales, similar to PCA but more robust to outliers.

The paper analyzes the spatio-temporal distribution and genogeographic affinity of mitochondrial DNA haplogroups in 24,216 Danes, finding increased frequencies of certain haplogroups linked to immigration.

The paper responds to criticism of male-biased admixture estimates from Bronze Age migrations by analyzing X-chromosomal and autosomal ancestry in ancient samples.

The paper attempts to replicate a genetic signal suggesting a sex bias in the Steppe migration into Central Europe using qpAdm, but does not confirm the original finding.

The paper reports European admixture in a 4000-year-old Chinchorro mummy, challenging the traditional view of pre-Columbian isolation.

This study analyzes 185 paleogenomic datasets to model ancient DNA decay, finding cytosine deamination follows a thermal age model but DNA fragmentation does not correlate with age.

The paper resequences mtDNA genomes of ancient Hungarian conquerors using NGS to correct inaccuracies in previously determined haplotypes from PCR-based methods.

The paper analyzes ancient genomes from the Pacific Northwest Coast to show genetic continuity over 10,000 years and population structure in the late Pleistocene.

ATLAS, a C++ toolkit that models post-mortem damage when genotyping ancient or low-depth BAM data, avoided GATK's reference bias and made fewer errors at higher depth in simulations.

This paper presents ancient DNA data from Northern Europe to reconstruct the genetic history of the region, showing earlier Anatolian farmer ancestry and the impact of steppe pastoralists.

The paper analyzes rare variant spectra across human populations, identifying two distinct mutation signatures linked to deamination and recent demography.

The paper identifies Thomas Kent's remains using a forced homozygote approach to estimate relatedness from degraded DNA, confirming his identity through simulated data.

This study uses DNA SatNav to trace the biogeographical origin of South Asian populations, finding ancient admixture between North and South Indian populations around 2300 years ago.

yHaplo walks the Y-chromosome tree with an error-tolerant breadth-first search, labelling the 1,244 1000 Genomes males in 20 seconds and matching every gold-standard call.