Forensic and Genetic Research

This study analyzes genomic data from 52 individuals across the central Southern Cone to trace genetic ancestry and movements during the Middle to Late Holocene.

This study analyzes ancient DNA from Iron Age Saka pastoralists in Kyrgyzstan, revealing genetic patterns consistent with patrilocality and female-mediated genetic diversity.

The paper integrates ancient genomic and phenotypic data to analyze stature in prehistoric Europeans, finding that lactase persistence alleles positively affect stature in ancient populations but not in modern ones.

This study identifies a fourth ancestral component in Dravidian-speaking tribes, suggesting a Proto-Dravidian ancestry originating around 4,400 years ago, distinct from other known sources.

The paper introduces a SLiM 5 model for simulating whole-genome human evolution, including sex chromosomes and mitochondrial DNA, and demonstrates its utility through simple analyses.

FLARE2 improves local ancestry inference by using haplotype clustering, enabling accurate results even when reference panels are poorly matched.

mrpast infers complex demographic histories from whole-genome genealogies, accurately recovering parameters like migration rates and population sizes in various models.

This study analyzes mitochondrial DNA variants and nuclear mitochondrial DNA segments in 7331 individuals from NyuWa and 1KGP, identifying common and ultra-rare NUMTs and linking mtDNA variants to nuclear DNA variants.

The paper uses ancient DNA from the Southern Urals to link the 10th century Hungarians to the Karayakupovo archaeological horizon.

The paper analyzes the genetic structure of a Sindhi population in West coast India, finding significant genetic affinity with the Burusho group and evidence of recent admixture with the Konkani population.

The paper presents genome-wide data from Gravettian-associated individuals and sedimentary DNA from the Solutrean period, revealing genetic admixture between East and West European populations before the Last Glacial Maximum.

The paper develops a method to estimate mutation age and population of origin in structured populations using genomic data and applies it to human skin pigmentation SNPs.

This paper shows that the likelihood ratios from IBDGem test a null hypothesis different from the traditional forensic one, potentially overestimating evidence strength for identity.

This study uses whole-genome sequencing of Central Asians to reveal genetic diversity, admixture events, and adaptive processes shaping their demographic history and medical relevance.

The paper presents genomic data from 1,031 individuals in the Tibetan-Yi Corridor, identifying genetic variants, adaptation signatures, and archaic introgression patterns.

The paper analyzes genome-wide data from Indigenous Patagonians to uncover genetic adaptations to cold, maritime diet, and pathogens, revealing prehistoric selection signals and admixture patterns.

This study models the Neolithic expansion of farmers in Europe, showing increasing admixture with hunter-gatherers over time and estimating farmer population size relative to hunter-gatherers.

This paper introduces DNANet, a U-Net-based deep learning model for automating allele calling in forensic DNA analysis, achieving performance comparable to human analysts.

This study uses ancient DNA to analyze post-Roman polity formation in the Little Hungarian Plain, revealing genetic changes and social organization patterns.

This study analyzes 68 ancient Portuguese genomes over 5,000 years, revealing migration patterns and genetic continuity, with influences from local, African, and Mediterranean populations.

DeepKin predicts relatedness from low-coverage genomes and paleogenomes using CNNs, achieving accuracy >90% with 10K shared SNPs and outperforming READv2.

This paper reanalyzes uniparental markers to argue that humans colonized the Americas before the Last Glacial Maximum, with post-LGM expansions starting in South America.

The paper introduces a SNP panel to reduce technology-specific bias in ancient DNA analysis, improving compatibility between different sequencing technologies and modern data.

This study shows that Near Eastern ancestry in Central Italy arrived during the late Republican period, before the Roman Empire began.

The Peruvian Genome Project collects and analyzes genomic data from native and mestizo populations in Peru to address underrepresentation in global genome databases and uncover genetic adaptations to local environments.

The paper analyzes ancient genomic data to show increased disease burden in human populations over the past 12,000 years, linked to cultural shifts and domestication.

This study analyzes genetic ancestry in the South African Coloured population, revealing regional variations and sex-biased admixture patterns.

This paper introduces as-eGRM, a method to reveal ancestry-specific structures in admixed populations by incorporating genealogical trees and local ancestry calls, outperforming existing methods in simulated and empirical datasets.

The paper estimates the probability of finding Y-STR profile matches and related individuals in forensic databases using simulation studies.

This paper introduces RAS, a statistical method for analyzing rare variants to detect population structure with higher resolution than common variants, and demonstrates its improved accuracy in ancestry proportion estimation.