Olfactory and Sensory Function Studies

This study shows that odor representations in the mouse piriform cortex drift over time, reducing classifier performance, and that continuous odor exposure slows but does not eliminate this drift.

This study investigates neural activation patterns in the olfactory epithelium of East African cichlids in response to odorants, revealing receptor-specific responses to amino acids and steroids.

This paper provides the first comprehensive RNA-seq analysis of the rabbit vomeronasal organ transcriptome, revealing age- and function-dependent gene expression patterns.

This study creates a comprehensive mouse olfactory ethological atlas using behavioral responses to 73 odorants, revealing shared properties between mouse and human olfactory perception.

This study shows freely-moving mice use sniff-synchronized nose movements to navigate odor gradients, identifying two distinct movement motifs during olfactory search.

This study investigates SARS-CoV-2 infection in the olfactory system, showing viral persistence and inflammation linked to prolonged loss of smell in COVID-19 patients.

The paper shows that odor identity can be decoded from bidirectional oscillatory communication between the olfactory bulb and piriform cortex in humans.

The paper shows that flow conditions during odor plume exposure affect the temporal representation of odor in the mouse olfactory bulb.

This study shows that insulin promotes the maturation of newly generated olfactory sensory neurons after injury, with a critical time window of days 8-13 post-injury.

The paper compares odor representation similarity across olfactory regions and finds that sparser activity in aPC and AON correlates with increased similarity despite fewer inputs from the OB.

The paper examines how nLOT neurons encode odor signals and behavioral states in mice during odor-guided tasks, finding bi-directional cue encoding and context-based odor-outcome associations.

The paper identifies TRPM5-expressing microvillous cells in the olfactory epithelium as potentially involved in viral infection through transcriptional profiling.

This study shows that innate odor preference in mice requires both spontaneous neural activity and sensory experience during a critical period, with ectopic projections altering odor valence.

This study investigates how long-range GABAergic inhibition from the basal forebrain modulates the activity and oscillations of mitral/tufted cells in the olfactory bulb.

The paper shows that running in mice changes spontaneous neural activity in the olfactory bulb, increasing population entropy and suggesting higher-order neuron interactions during locomotion.

The paper shows that innate odor valence is not encoded through insulated channels but is instead re-coded via crosstalk among mitral/tufted cells in the olfactory bulb, abolishing innate behavioral responses to mixed odors.

The paper identifies a rare olfactory rod cell type in larval zebrafish with an actin-rich apical projection, distinct from known olfactory sensory neurons and other sensory cells.

This study investigates how larval zebrafish integrate binasal chemosensory inputs to guide avoidance behavior using microfluidics and brainwide imaging.

This study identifies nuclear architecture disruption as a mechanism underlying SARS-CoV-2 induced anosmia by analyzing human and hamster olfactory tissues.

The paper analyzes natural variants in human olfactory receptors to reveal diversity and functional implications of mutations across populations.

This study investigates how male brains respond to body odors of ovulating and pregnant women, finding distinct neural activations linked to sexual availability and pregnancy detection.

This study examines olfactory network functional connectivity in Parkinson's disease subtypes, finding impaired connectivity in akinetic-rigid patients linked to worse clinical outcomes.

This study shows that the human olfactory bulb processes odor valence through gamma and beta activity, with negative odors triggering motor avoidance behavior.

The paper develops a Python program to automate the quantification of glomeruli features in mouse olfactory bulbs, validated for efficiency and accuracy in genetic studies.

The paper investigates inhibitory signaling in mammalian olfactory transduction mediated by Gαo, showing PI3K-dependent inhibition in ORNs lacking Go.

This study shows zebrafish larvae detect salt gradients using olfactory receptor neurons that sense monovalent ions, avoiding high salinity environments.

This study examines olfactory perception decline and frontal oscillation deficits as markers for Alzheimer's disease using EEG and behavioral tests in an Iranian population.

The paper characterizes buffalo nasal epithelial odorant binding proteins (OBPs), identifies key residues involved in pheromone binding, and validates their function through in-silico and biochemical methods.

The paper presents a Hebbian-type model of structural synaptic plasticity in the olfactory bulb that explains how learning enhances discriminability of similar stimuli while reducing that of dissimilar ones.