Eric D. Larson

The paper shows that exposure to Prevotella melaninogenica reprograms myeloid cells to enhance defense against Streptococcus pneumoniae lung infection.

PDGFR/{beta} heterodimer binding to MYO1D promotes rapid internalization, inhibiting ERK1/2 phosphorylation and reducing cell proliferation.

This study shows PDGFRα signaling regulates Srsf3 binding to transcripts, affecting PI3K signaling and endosomal trafficking in craniofacial development.

The paper shows that high Sox2 expression in lingual progenitors predicts their ability to generate taste receptor cells and lingual epithelium in vitro.

This study identifies Srsf3 as a regulator of alternative RNA splicing downstream of PDGFRα signaling, which is critical for craniofacial development.

The paper shows taste bud cell renewal begins at birth and SHH signaling shifts from repressing to promoting taste cell differentiation.

The paper identifies TRPM5-expressing microvillous cells in the olfactory epithelium as potentially involved in viral infection through transcriptional profiling.

The paper tests GAD65Cre as a reporter for Type I taste cells and finds it drives expression in multiple cell types, making it unreliable for specific function studies.

The paper performs single-cell RNA sequencing on geniculate ganglion neurons to analyze taste modality-specific clusters and compares results with prior studies.

The paper identifies a subset of olfactory and vomeronasal sensory neurons expressing Foxj1-driven eGFP, lacking motile cilia but showing distinct spatial distribution and axonal termination patterns.

The paper examines mucin expression differences between olfactory and respiratory epithelium in mice and finds no radiation-induced changes in mucin expression after 8 Gy exposure.